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Mechanisms underlying mechanical sensitization induced by complement C5a: the roles of macrophages, TRPV1 and CGRP receptors

The complement system significantly contributes to the development of inflammatory and neuropathic pain, but the underlying mechanisms are poorly understood. Recently, we identified the signaling pathway responsible for thermal hypersensitivity induced by the complement system component C5a. Here, w...

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Detalhes bibliográficos
Publicado no:Pain
Main Authors: Warwick, Charles A., Shutov, Leonid P., Shepherd, Andrew J., Mohapatra, Durga P., Usachev, Yuriy M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377341/
https://ncbi.nlm.nih.gov/pubmed/30507785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000001449
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