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SAMHD1 Suppression of Antiviral Immune Responses

SAMHD1 is a host triphosphohydrolase that degrades intracellular deoxynucleoside triphosphates (dNTPs) to a lower level that restricts viral DNA synthesis, and thus prevents replication of diverse viruses in non-dividing cells. Recent progress indicates that SAMHD1 negatively regulates antiviral inn...

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Bibliografski detalji
Izdano u:Trends Microbiol
Glavni autori: Chen, Shuliang, Bonifati, Serena, Qin, Zhihua, Gelais, Corine St., Wu, Li
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377309/
https://ncbi.nlm.nih.gov/pubmed/30336972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tim.2018.09.009
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