The association between endogenous opioid function and morphine responsiveness: a moderating role for endocannabinoids?

We sought to replicate prior findings that low endogenous opioid (EO) function predicts greater morphine analgesia, and extended these findings by examining whether circulating endocannabinoids and related lipids moderate EO-related predictive effects. Individuals with chronic low back pain (n=46) p...

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Detalhes bibliográficos
Publicado no:Pain
Main Authors: Bruehl, Stephen, Burns, John W., Morgan, Amanda, Koltyn, Kelli, Gupta, Rajnish, Buvanendran, Asokumar, Edwards, David, Chont, Melissa, Kingsley, Philip J., Marnett, Larry, Stone, Amanda, Patel, Sachin
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377294/
https://ncbi.nlm.nih.gov/pubmed/30562268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000001447
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