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A systematically-revised ribosome profiling method for bacteria reveals pauses at single-codon resolution

In eukaryotes, ribosome profiling provides insight into the mechanism of protein synthesis at the codon level. In bacteria, however, the method has been more problematic and no consensus has emerged for how to best prepare profiling samples. Here, we identify the sources of these problems and descri...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Mohammad, Fuad, Green, Rachel, Buskirk, Allen R
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377232/
https://ncbi.nlm.nih.gov/pubmed/30724162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.42591
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