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Antibody Targets on the Surface of Plasmodium falciparum–Infected Erythrocytes That Are Associated With Immunity to Severe Malaria in Young Children

BACKGROUND: Sequestration of Plasmodium falciparum–infected erythrocytes (IEs) in the microvasculature contributes to pathogenesis of severe malaria in children. This mechanism is mediated by antigens expressed on the IE surface. However, knowledge of specific targets and functions of antibodies to...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Chan, Jo-Anne, Boyle, Michelle J, Moore, Kerryn A, Reiling, Linda, Lin, Zaw, Hasang, Wina, Avril, Marion, Manning, Laurens, Mueller, Ivo, Laman, Moses, Davis, Timothy, Smith, Joseph D, Rogerson, Stephen J, Simpson, Julie A, Fowkes, Freya J I, Beeson, James G
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376912/
https://ncbi.nlm.nih.gov/pubmed/30365004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy580
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