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Exploring Polypharmacology in Drug Discovery and Repurposing Using the CANDO Platform
BACKGROUND: Traditional drug discovery approaches focus on a limited set of target molecules for treatment against specific indications/diseases. However, drug absorption, dispersion, metabolism, and excretion (ADME) involve interactions with multiple protein systems. Drugs approved for particular i...
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| Vydáno v: | Curr Pharm Des |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6376875/ https://ncbi.nlm.nih.gov/pubmed/27013226 |
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