Comprehensive gene expression meta-analysis identifies signature genes that distinguish microglia from peripheral monocytes/macrophages in health and glioma

Monocytes/macrophages have begun to emerge as key cellular modulators of brain homeostasis and central nervous system (CNS) disease. In the healthy brain, resident microglia are the predominant macrophage cell population; however, under conditions of blood-brain barrier leakage, peripheral monocytes...

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Bibliografiske detaljer
Udgivet i:Acta Neuropathol Commun
Main Authors: Haage, Verena, Semtner, Marcus, Vidal, Ramon Oliveira, Hernandez, Daniel Perez, Pong, Winnie W., Chen, Zhihong, Hambardzumyan, Dolores, Magrini, Vincent, Ly, Amy, Walker, Jason, Mardis, Elaine, Mertins, Philipp, Sauer, Sascha, Kettenmann, Helmut, Gutmann, David H.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376799/
https://ncbi.nlm.nih.gov/pubmed/30764877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0665-y
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