DLA class II risk haplotypes for autoimmune diseases in the bearded collie offer insight to autoimmunity signatures across dog breeds

BACKGROUND: Primary hypoadrenocorticism (Addison’s disease, AD) and symmetrical lupoid onychodystrophy (SLO) are two clinical conditions with an autoimmune etiology that occur in multiple dog breeds. In man, autoimmunity is associated with polymorphisms in immune-related genes that result in a reduc...

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Detalhes bibliográficos
Publicado no:Canine Genet Epidemiol
Main Authors: Gershony, Liza C., Belanger, Janelle M., Short, Andrea D., Le, Myly, Hytönen, Marjo K., Lohi, Hannes, Famula, Thomas R., Kennedy, Lorna J., Oberbauer, Anita M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376674/
https://ncbi.nlm.nih.gov/pubmed/30783534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40575-019-0070-7
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