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Perivascular Dendritic Cells Elicit Anaphylaxis by Relaying Allergens to Mast Cells via Microvesicles
Anaphylactic reactions are triggered when allergens enter the blood circulation and activate IgE-sensitized mast cells (MCs) causing systemic discharge of prestored proinflammatory mediators. Since MCs are extravascular, how they perceive circulating allergens remains a conundrum. Here, we describe...
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| Publicado no: | Science |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6376486/ https://ncbi.nlm.nih.gov/pubmed/30409859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aao0666 |
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