LINC01554-Mediated Glucose Metabolism Reprogramming Suppresses Tumorigenicity in Hepatocellular Carcinoma via Downregulating PKM2 Expression and Inhibiting Akt/mTOR Signaling Pathway

Background and Aims: Cancer cells prefer aerobic glycolysis to maintain growth advantages, but the role of long non-coding RNAs (lncRNAs) in glycometabolism still remains unclear. Here we identified one cytoplasmic lncRNA LINC01554 as a significantly downregulated lncRNA in hepatocellular carcinoma...

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Publicat a:Theranostics
Autors principals: Zheng, Yin-Li, Li, Lei, Jia, Yong-Xun, Zhang, Bao-Zhu, Li, Jiang-Chao, Zhu, Ying-Hui, Li, Meng-Qing, He, Jiao-Zi, Zeng, Ting-Ting, Ban, Xiao-Jiao, Yuan, Yun-Fei, Li, Yan, Guan, Xin-Yuan
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2019
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376468/
https://ncbi.nlm.nih.gov/pubmed/30809309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.28992
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