RACK1 Promotes Self-Renewal and Chemoresistance of Cancer Stem Cells in Human Hepatocellular Carcinoma through Stabilizing Nanog

Targeting cancer stem cells (CSCs) has been proposed as a new strategy to eradicate malignancies, including hepatocellular carcinoma (HCC). However, the mechanisms by which CSCs sustain their self-renewal and chemoresistance remain elusive. Nanog is a master transcriptional regulator of stemness, es...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Cao, Junxia, Zhao, Min, Liu, Jian, Zhang, Xueying, Pei, Yujun, Wang, Jingyang, Yang, Xiao, Shen, Beifen, Zhang, Jiyan
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376462/
https://ncbi.nlm.nih.gov/pubmed/30809310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.29271
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