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Novel column generation-based optimization approach for poly-pathway kinetic model applied to CHO cell culture
Mathematical modelling can provide precious tools for bioprocess simulation, prediction, control and optimization of mammalian cell-based cultures. In this paper we present a novel method to generate kinetic models of such cultures, rendering complex metabolic networks in a poly-pathway kinetic mode...
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| Publicado no: | Metab Eng Commun |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6376161/ https://ncbi.nlm.nih.gov/pubmed/30809468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mec.2018.e00083 |
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