Cold Tumors: A Therapeutic Challenge for Immunotherapy

Therapeutic monoclonal antibodies targeting immune checkpoints (ICPs) have changed the treatment landscape of many tumors. However, response rate remains relatively low in most cases. A major factor involved in initial resistance to ICP inhibitors is the lack or paucity of tumor T cell infiltration,...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Bonaventura, Paola, Shekarian, Tala, Alcazer, Vincent, Valladeau-Guilemond, Jenny, Valsesia-Wittmann, Sandrine, Amigorena, Sebastian, Caux, Christophe, Depil, Stéphane
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376112/
https://ncbi.nlm.nih.gov/pubmed/30800125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00168
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