Indispensable role of β-arrestin2 in the protection of remifentanil preconditioning against hepatic ischemic reperfusion injury

Our previous study demonstrated that remifentanil, an opioid agonist, conferred profound liver protection during hepatic ischemia reperfusion injury (HIRI), in which Toll-like receptors (TLRs) played a crucial role in mediating the inflammatory responses. β-arrestin2, a well-known mu opioid receptor...

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Udgivet i:Sci Rep
Main Authors: Yang, Yuting, Chen, Caiyang, Cui, Cui, Jiao, Yingfu, Li, Peiying, Zhu, Ling, Yu, Weifeng, Xia, Qiang, Wen, Daxiang, Yang, Liqun
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376065/
https://ncbi.nlm.nih.gov/pubmed/30765766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-38456-9
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