Targeting Epidermal Growth Factor Receptor (EGFR) and Human Epidermal Growth Factor Receptor 2 (HER2) Expressing Bladder Cancer Using Combination Photoimmunotherapy (PIT)

Bladder cancer (BC) is heterogeneous and expresses various cell surface targets. Photoimmunotherapy (PIT) involves monoclonal antibodies (MAbs) conjugated to a photoabsorber (PA), IR Dye 700Dx, and then activated by near infra-red light (NIR) to specifically target tumors. We have demonstrated that...

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Publicat a:Sci Rep
Autors principals: Siddiqui, Mohammad R., Railkar, Reema, Sanford, Thomas, Crooks, Daniel R., Eckhaus, Michael A., Haines, Diana, Choyke, Peter L., Kobayashi, Hisataka, Agarwal, Piyush K.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375935/
https://ncbi.nlm.nih.gov/pubmed/30765854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-38575-x
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