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Mechanisms contributing to persistently activated cell phenotypes in pulmonary hypertension

Chronic pulmonary hypertension (PH) is characterized by the accumulation of persistently activated cell types in the pulmonary vessel exhibiting aberrant expression of genes involved in apoptosis resistance, proliferation, inflammation and extracellular matrix (ECM) remodelling. Current therapies fo...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Hu, Cheng‐Jun, Zhang, Hui, Laux, Aya, Pullamsetti, Soni S., Stenmark, Kurt R.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375873/
https://ncbi.nlm.nih.gov/pubmed/29920674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP275857
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