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Using Bayes Model Averaging to Leverage Both Gene Main Effects and GxE Interactions to Identify Genomic Regions in Genome-Wide Association Studies
Genome-wide association studies (GWAS) typically search for marginal associations between a single nucleotide polymorphism (SNP) and a disease trait while gene-environment (GxE) interactions remain generally unexplored. More powerful methods beyond the simple case-control approach leverage either ma...
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| Опубликовано в: : | Genet Epidemiol |
|---|---|
| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6375769/ https://ncbi.nlm.nih.gov/pubmed/30456811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22171 |
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