Relationships between Adipose Mitochondrial Function, Serum Adiponectin, and Insulin Resistance in Persons with HIV after 96 weeks of Antiretroviral Therapy

OBJECTIVE: Some antiretroviral therapy (ART) and HIV itself confer metabolic risk, perhaps through altered mitochondrial function and adipokines. In ACTG study A5224s, adipose mitochondrial DNA (mtDNA) levels decreased on ART, and electron transport chain complex I (CI) and IV (CIV) activity decreas...

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Detalhes bibliográficos
Publicado no:J Acquir Immune Defic Syndr
Main Authors: HULGAN, Todd, RAMSEY, Benjamin S., KOETHE, John R., SAMUELS, David C., GERSCHENSON, Mariana, LIBUTTI, Daniel E., SAX, Paul E., DAAR, Eric S., McCOMSEY, Grace A., BROWN, Todd T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375746/
https://ncbi.nlm.nih.gov/pubmed/30531304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000001926
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