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A novel cell-free method to culture Schistosoma mansoni from cercariae to juvenile worm stages for in vitro drug testing

BACKGROUND: The arsenal in anthelminthic treatment against schistosomiasis is limited and relies almost exclusively on a single drug, praziquantel (PZQ). Thus, resistance to PZQ could constitute a major threat. Even though PZQ is potent in killing adult worms, its activity against earlier stages is...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Frahm, Sören, Anisuzzaman, Anisuzzaman, Prodjinotho, Ulrich Fabien, Vejzagić, Nermina, Verschoor, Admar, Prazeres da Costa, Clarissa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375649/
https://ncbi.nlm.nih.gov/pubmed/30689639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006590
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