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The cAMP effectors, Rap2b and EPAC, are involved in the regulation of the development of the Coxiella burnetii containing vacuole by altering the fusogenic capacity of the vacuole

Cyclic Adenosine 3′,5′-monophosphate (cAMP) is a key second messenger known to directly regulate not only the protein kinase A (PKA) activity but also other important molecules such as the exchange protein activated by cAMP (EPAC), which is as a guanine nucleotide exchange factor (GEF) of the low mo...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mansilla Pareja, María Eugenia, Gaurón, Maria Celeste, Robledo, Esteban, Aguilera, Milton Osmar, Colombo, María Isabel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375611/
https://ncbi.nlm.nih.gov/pubmed/30763357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0212202
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