Serum amyloid A and Janus kinase 2 in a mouse model of diabetic kidney disease

BACKGROUND: Serum amyloid A (SAA), a potent inflammatory mediator, and Janus kinase 2 (JAK2), an intracellular signaling kinase, are increased by diabetes. The aims were to elucidate: 1) a JAK2-mediated pathway for increased SAA in the kidneys of diabetic mice; 2) a JAK2-SAA pathway for inflammation...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Dieter, Brad P., Meek, Rick L., Anderberg, Robert J., Cooney, Sheryl K., Bergin, Jen L., Zhang, Hongyu, Nair, Viji, Kretzler, Matthias, Brosius, Frank C., Tuttle, Katherine R.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2019
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375550/
https://ncbi.nlm.nih.gov/pubmed/30763329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0211555
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