Alternative (backdoor) androgen production and masculinization in the human fetus

Masculinization of the external genitalia in humans is dependent on formation of 5α-dihydrotestosterone (DHT) through both the canonical androgenic pathway and an alternative (backdoor) pathway. The fetal testes are essential for canonical androgen production, but little is known about the synthesis...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: O’Shaughnessy, Peter J., Antignac, Jean Philippe, Le Bizec, Bruno, Morvan, Marie-Line, Svechnikov, Konstantin, Söder, Olle, Savchuk, Iuliia, Monteiro, Ana, Soffientini, Ugo, Johnston, Zoe C., Bellingham, Michelle, Hough, Denise, Walker, Natasha, Filis, Panagiotis, Fowler, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375548/
https://ncbi.nlm.nih.gov/pubmed/30763313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000002
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