Cognitive and Pathological Influences of Tau Pathology in Lewy Body Disorders

OBJECTIVE: To use digital histology in a large autopsy cohort of Lewy Body Disorder (LBD) patients with dementia to test the hypotheses that co-occurring Alzheimer’s disease (AD) pathology impacts the anatomic distribution of α-synuclein (SYN) pathology and that co-occurring neocortical tau patholog...

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Veröffentlicht in:Ann Neurol
Hauptverfasser: Coughlin, David G., Xie, Sharon X., Liang, Mendy, Williams, Andrew, Peterson, Claire, Weintraub, Daniel, McMillan, Corey T., Wolk, David A., Akhtar, Rizwan S., Hurtig, Howard, Coslett, H. Branch, Hamilton, Roy, Siderowf, Andrew, Duda, John E., Rascovsky, Katya, Lee, Edward B., Lee, Virginia M.-Y., Grossman, Murray, Trojanowski, John Q., Irwin, David J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375484/
https://ncbi.nlm.nih.gov/pubmed/30549331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25392
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