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Responses of perivascular macrophages to circulating lipopolysaccharides in the subfornical organ with special reference to endotoxin tolerance

BACKGROUND: Circulating endotoxins including lipopolysaccharides (LPS) cause brain responses such as fever and decrease of food and water intake, while pre-injection of endotoxins attenuates these responses. This phenomenon is called endotoxin tolerance, but the mechanisms underlying it remain uncle...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Morita-Takemura, Shoko, Nakahara, Kazuki, Hasegawa-Ishii, Sanae, Isonishi, Ayami, Tatsumi, Kouko, Okuda, Hiroaki, Tanaka, Tatsuhide, Kitabatake, Masahiro, Ito, Toshihiro, Wanaka, Akio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375194/
https://ncbi.nlm.nih.gov/pubmed/30764851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1431-6
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