Genetic deletion of genes in the cerebellar rhombic lip lineage can stimulate compensation through adaptive reprogramming of ventricular zone-derived progenitors

BACKGROUND: The cerebellum is a foliated posterior brain structure involved in coordination of motor movements and cognition. The cerebellum undergoes rapid growth postnataly due to Sonic Hedgehog (SHH) signaling-dependent proliferation of ATOH1+ granule cell precursors (GCPs) in the external granul...

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Dades bibliogràfiques
Publicat a:Neural Dev
Autors principals: Wojcinski, Alexandre, Morabito, Morgane, Lawton, Andrew K., Stephen, Daniel N., Joyner, Alexandra L.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375182/
https://ncbi.nlm.nih.gov/pubmed/30764875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13064-019-0128-y
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