Gadolinium-doped bioglass scaffolds promote osteogenic differentiation of hBMSC via the Akt/GSK3β pathway and facilitate bone repair in vivo

BACKGROUND: Biomaterial-induced osteogenesis is mainly related to hierarchically porous structures and bioactive components. Rare earth elements are well known to promote osteogenesis and stimulate bone repair; however, the underlying biological effects of gadolinium (Gd) element on bone regeneratio...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Zhu, Dao-Yu, Lu, Bin, Yin, Jun-Hui, Ke, Qin-Fei, Xu, He, Zhang, Chang-Qing, Guo, Ya-Ping, Gao, You-Shui
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375113/
https://ncbi.nlm.nih.gov/pubmed/30804672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S193576
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