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Rapamycin as a potential treatment for succinate dehydrogenase deficiency

Drosophila melanogaster is a powerful model to study mitochondrial respiratory chain defects, particularly succinate dehydrogenase (SDH) deficiency. Mutations in sdh genes cause degenerative disorders and often lead to death. Therapies for such pathologies are based on a combination of vitamins and...

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書目詳細資料
發表在:Heliyon
Main Authors: Fan, Frances, Sam, Rheba, Ryan, Emma, Alvarado, Katherine, Villa-Cuesta, Eugenia
格式: Artigo
語言:Inglês
出版: Elsevier 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6374580/
https://ncbi.nlm.nih.gov/pubmed/30805566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2019.e01217
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