Effect of Age, High-Fat Diet, and Rat Strain on Serum Biomarkers and Telomere Length and Global DNA Methylation in Peripheral Blood Mononuclear Cells

The objective of the current study was to determine if age, diet, and genetic disposition (animal strain) in an animal model had early effects on specific molecular markers in circulating peripheral blood mononuclear cells (PBMCs). Three strains [Sprague-Dawley (SD), Fischer 344 (F344), and Brown-No...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Antonini, James M., Kodali, Vamsi, Meighan, Terence G., Roach, Katherine A., Roberts, Jenny R., Salmen, Rebecca, Boyce, Greg R., Zeidler-Erdely, Patti C., Kashon, Michael, Erdely, Aaron, Shoeb, Mohammad
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6374545/
https://ncbi.nlm.nih.gov/pubmed/30760804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-38192-0
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