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Expression, activity and localization of lysosomal sulfatases in Chronic Obstructive Pulmonary Disease

Chronic obstructive pulmonary disease (COPD) is a leading cause of death world-wide. Recently, we showed that COPD is associated with gene polymorphisms in SUMF1, a master regulator of sulfatases. Sulfatases are involved in extracellular matrix remodeling and activated by SUMF1, but their role in th...

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Vydáno v:Sci Rep
Hlavní autoři: Weidner, Julie, Jogdand, Prajakta, Jarenbäck, Linnea, Åberg, Ida, Helihel, Dalja, Ankerst, Jaro, Westergren-Thorsson, Gunilla, Bjermer, Leif, Erjefält, Jonas S., Tufvesson, Ellen
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6374378/
https://ncbi.nlm.nih.gov/pubmed/30760748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37958-w
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