Free Polyethylenimine Enhances Substrate-Mediated Gene Delivery on Titanium Substrates Modified With RGD-Functionalized Poly(acrylic acid) Brushes

Substrate mediated gene delivery (SMD) is a method of immobilizing DNA complexes to a substrate via covalent attachment or nonspecific adsorption, which allows for increased transgene expression with less DNA compared to traditional bolus delivery. It may also increase cells receptivity to transfect...

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Udgivet i:Front Chem
Main Authors: Mantz, Amy, Rosenthal, Alice, Farris, Eric, Kozisek, Tyler, Bittrich, Eva, Nazari, Saghar, Schubert, Eva, Schubert, Mathias, Stamm, Manfred, Uhlmann, Petra, Pannier, Angela K.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Chemistry
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6374293/
https://ncbi.nlm.nih.gov/pubmed/30792979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2019.00051
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