Leukemia Inhibitory Factor Functions in Parallel with Interleukin-6 to Promote Ovarian Cancer Growth

Ovarian carcinoma-associated mesenchymal stem cells (CA-MSC) produce not only high levels of IL6 but also the related cytokine leukemia inhibitory factor (LIF). Interleukin 6 (IL6) mediated activation of STAT3 is implicated as a critical therapeutic target for cancer therapy. Less is known about the...

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Bibliografiske detaljer
Udgivet i:Oncogene
Main Authors: McLean, Karen, Tan, Lijun, Bolland, Danielle E., Coffman, Lan G., Peterson, Luke F., Talpaz, Moshe, Neamati, Nouri, Buckanovich, Ronald J.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6374186/
https://ncbi.nlm.nih.gov/pubmed/30305729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0523-6
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