Analytical characterization and reference interval of an enzyme-linked immunosorbent assay for active von Willebrand factor

BACKGROUND: Interaction of von Willebrand factor (VWF) with platelets requires a conformational change that exposes an epitope within the VWF A1 domain, enabling platelet glycoprotein Ibα binding. Quantification of this ‘‘active” conformation of VWF has been shown to provide pathophysiological insig...

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Publicado en:PLoS One
Autores principales: van der Vorm, Lisa N., Li, Li, Huskens, Dana, Chayouâ, Walid, Kelchtermans, Hilde, de Groot, Philip G., Roest, Mark, Remijn, Jasper A., de Laat, Bas
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2019
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6373957/
https://ncbi.nlm.nih.gov/pubmed/30759116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0211961
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