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Calpain cleaves phospholipid flippase ATP8A1 during apoptosis in platelets
The asymmetric distribution of phospholipids in the plasma/organellar membranes is generated and maintained through phospholipid flippases in resting cells, but becomes disrupted in apoptotic cells and activated platelets, resulting in phosphatidylserine (PS) exposure on the cell surface. Stable PS...
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| Publicado no: | Blood Adv |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6373741/ https://ncbi.nlm.nih.gov/pubmed/30674456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018023473 |
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