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Excitation of Cortical nNOS/NK1R Neurons by Hypocretin 1 is Independent of Sleep Homeostasis

We have proposed that cortical nNOS/NK1R interneurons have a role in sleep homeostasis. The hypocretins (orexins) are wake-promoting neuropeptides and hypocretin/orexin (Hcrt) neurons project to the cortex. Hcrt peptides affect deep layer cortical neurons, and Hcrt receptor 1 (Hcrtr1; Ox1r) mRNA is...

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Bibliografiske detaljer
Udgivet i:Cereb Cortex
Main Authors: Williams, Rhîannan H, Black, Sarah W, Thomas, Alexia M, Piquet, Juliette, Cauli, Bruno, Kilduff, Thomas S
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6373683/
https://ncbi.nlm.nih.gov/pubmed/29462275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhy015
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