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Population Pharmacokinetics of the Interleukin-23 Inhibitor Risankizumab in Subjects with Psoriasis and Crohn’s Disease: Analyses of Phase I and II Trials

BACKGROUND AND OBJECTIVES: Risankizumab is a humanized anti-interleukin-23 monoclonal antibody in development for the treatment of several inflammatory diseases. This work characterized the pharmacokinetics of risankizumab and evaluated covariates that may affect its exposures using phase I and II t...

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Bibliografske podrobnosti
izdano v:Clin Pharmacokinet
Main Authors: Suleiman, Ahmed A., Khatri, Amit, Minocha, Mukul, Othman, Ahmed A.
Format: Artigo
Jezik:Inglês
Izdano: Springer International Publishing 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6373392/
https://ncbi.nlm.nih.gov/pubmed/30123942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-018-0704-z
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