Polygenic Risk Score for Alzheimer’s Disease: Implications for Memory Performance and Hippocampal Volumes in Early Life

OBJECTIVE: Alzheimer’s disease is a heritable neurodegenerative disorder in which early-life precursors may manifest in cognition and brain structure. The authors evaluate this possibility by examining, in youths, associations among polygenic risk score for Alzheimer’s disease, cognitive abilities,...

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Bibliografski detalji
Izdano u:Am J Psychiatry
Glavni autori: Axelrud, Luiza K., Santoro, Marcos L., Pine, Daniel S., Talarico, Fernanda, Gadelha, Ary, Manfro, Gisele G., Pan, Pedro M., Jackowski, Andrea, Picon, Felipe, Brietzke, Elisa, Grassi-Oliveira, Rodrigo, Bressan, Rodrigo A., Miguel, Eurípedes C., Rohde, Luis A., Hakonarson, Hakon, Pausova, Zdenka, Belangero, Sintia, Paus, Tomas, Salum, Giovanni A.
Format: Artigo
Jezik:Inglês
Izdano: 2018
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6372950/
https://ncbi.nlm.nih.gov/pubmed/29495896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1176/appi.ajp.2017.17050529
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