Herpes Simplex Virus 1 Lytic Infection Blocks MicroRNA (miRNA) Biogenesis at the Stage of Nuclear Export of Pre-miRNAs

Herpes simplex virus 1 (HSV-1) switches between two infection programs, productive (“lytic”) and latent infection. Some HSV-1 microRNAs (miRNAs) have been hypothesized to help control this switch, and yet little is known about regulation of their expression. Using Northern blot analyses, we found th...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Pan, Dongli, Li, Gang, Morris-Love, Jenna, Qi, Shuyuan, Feng, Lei, Mertens, Max E., Jurak, Igor, Knipe, David M., Coen, Donald M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6372804/
https://ncbi.nlm.nih.gov/pubmed/30755517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02856-18
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