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Pathogenic function of bystander-activated memory-like CD4(+) T cells in autoimmune encephalomyelitis
T cells generate antigen-specific immune responses to their cognate antigen as a hallmark of adaptive immunity. Despite the importance of antigen-specific T cells, here we show that antigen non-related, bystander memory-like CD4(+) T cells also significantly contribute to autoimmune pathogenesis. Tr...
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| Veröffentlicht in: | Nat Commun |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6372661/ https://ncbi.nlm.nih.gov/pubmed/30755603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08482-w |
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