Genomic Characteristics of Myeloproliferative Neoplasms in Patients Exposed to Ionizing Radiation following the Chernobyl Nuclear Accident

Myeloproliferative neoplasms (MPNs) driver mutations are usually found in JAK2, MPL and CALR genes, however, 10–15% of cases are triple negative (TN). A previous study showed lower rate of JAK2 V617F in Primary Myelofibrosis (PMF) patients exposed to low doses of ionizing radiation (IR) from Chernob...

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Publicat a:Am J Hematol
Autors principals: Poluben, Larysa, Puligandla, Maneka, Neuberg, Donna, Bryke, Christine R., Hsu, Yahsuan, Shumeiko, Oleksandr, Yuan, Xin, Voznesensky, Olga, Pihan, German, Adam, Miriam, Fraenkel, Ernest, Rasnic, Roni, Linial, Michal, Klymenko, Sergiy, Balk, Steven P., Fraenkel, Paula G.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6371805/
https://ncbi.nlm.nih.gov/pubmed/30295334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.25307
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