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The phylogeny of 48 alleles, experimentally verified at 21 kb, and its application to clinical allele detection

BACKGROUND: Sequence information generated from next generation sequencing is often computationally phased using haplotype-phasing algorithms. Utilizing experimentally derived allele or haplotype information improves this prediction, as routinely used in HLA typing. We recently established a large d...

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Détails bibliographiques
Publié dans:J Transl Med
Auteurs principaux: Srivastava, Kshitij, Wollenberg, Kurt R., Flegel, Willy A.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6371619/
https://ncbi.nlm.nih.gov/pubmed/30744658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-1791-9
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