Neuroactive Steroids Reverse Tonic Inhibitory Deficits in Fragile X Syndrome Mouse Model

Fragile X syndrome (FXS) is the most common form of inherited intellectual disability. A reduction in neuronal inhibition mediated by γ-aminobutyric acid type A receptors (GABA(A)Rs) has been implicated in the pathophysiology of FXS. Neuroactive steroids (NASs) are known allosteric modulators of GAB...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Modgil, Amit, Vien, Thuy N., Ackley, Michael A., Doherty, James J., Moss, Stephen J., Davies, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6371020/
https://ncbi.nlm.nih.gov/pubmed/30804752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00015
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados