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High glutathionylation of placental endothelial nitric oxide synthase in preeclampsia

Decreased nitric oxide (NO) bioavailability plays a critical role in the pathophysiology of preeclampsia (PE). Recent evidence indicates that S-glutathionylation may occur on the endothelial nitric oxide synthase (eNOS), leading to eNOS uncoupling, characterized by a decreased NO production and an i...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Guerby, Paul, Swiader, Audrey, Augé, Nathalie, Parant, Olivier, Vayssière, Christophe, Uchida, Koji, Salvayre, Robert, Negre-Salvayre, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370867/
https://ncbi.nlm.nih.gov/pubmed/30738311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101126
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