Altered mitochondrial quality control in Atg7-deficient VSMCs promotes enhanced apoptosis and is linked to unstable atherosclerotic plaque phenotype

Vascular smooth muscle cells (VSMCs) are one of the main cellular determinants in arterial pathology. A large body of evidence indicates that death of VSMCs is associated with features of high-risk/vulnerable atherosclerotic plaques. Mitochondrial turnover is an essential aspect of the mitochondrial...

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Publicat a:Cell Death Dis
Autors principals: Nahapetyan, Hripsimé, Moulis, Manon, Grousset, Elisa, Faccini, Julien, Grazide, Marie-Hélène, Mucher, Elodie, Elbaz, Meyer, Martinet, Wim, Vindis, Cécile
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370858/
https://ncbi.nlm.nih.gov/pubmed/30741928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1400-0
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