c-Myc inhibits myoblast differentiation and promotes myoblast proliferation and muscle fibre hypertrophy by regulating the expression of its target genes, miRNAs and lincRNAs

The transcription factor c-Myc is an important regulator of cellular proliferation, differentiation and embryogenesis. While c-Myc can inhibit myoblast differentiation, the underlying mechanisms remain poorly understood. Here, we found that c-Myc does not only inhibits myoblast differentiation but a...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Luo, Wen, Chen, Jiahui, Li, Limin, Ren, Xueyi, Cheng, Tian, Lu, Shiyi, Lawal, Raman Akinyanju, Nie, Qinghua, Zhang, Xiquan, Hanotte, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370811/
https://ncbi.nlm.nih.gov/pubmed/29786076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0129-0
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