Glucocorticoid receptor in astrocytes regulates midbrain dopamine neurodegeneration through connexin hemichannel activity

The precise contribution of astrocytes in neuroinflammatory process occurring in Parkinson’s disease (PD) is not well characterized. In this study, using GR(Cx30CreERT2) mice that are conditionally inactivated for glucocorticoid receptor (GR) in astrocytes, we have examined the actions of astrocytic...

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Gepubliceerd in:Cell Death Differ
Hoofdauteurs: Maatouk, Layal, Yi, Chenju, Carrillo-de Sauvage, Maria-Angeles, Compagnion, Anne-Claire, Hunot, Stéphane, Ezan, Pascal, Hirsch, Etienne C., Koulakoff, Annette, Pfrieger, Frank W, Tronche, François, Leybaert, Luc, Giaume, Christian, Vyas, Sheela
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370798/
https://ncbi.nlm.nih.gov/pubmed/30006609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0150-3
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