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The Downregulation of MicroRNA hsa-miR-340-5p in IAV-Infected A549 Cells Suppresses Viral Replication by Targeting RIG-I and OAS2

The influenza A virus poses serious public health challenges worldwide. Strikingly, small noncoding microRNAs (miRNAs) that modulate gene expression are closely involved in antiviral responses, although the underlying mechanisms are essentially unknown. We now report that microRNA-340 (miR340) is do...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Ther Nucleic Acids
Prif Awduron: Zhao, Lianzhong, Zhang, Xiaohan, Wu, Zhu, Huang, Kun, Sun, Xiaomei, Chen, Huanchun, Jin, Meilin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Gene & Cell Therapy 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370596/
https://ncbi.nlm.nih.gov/pubmed/30753994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.12.014
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