Evidence of early microstructural white matter abnormalities in multiple sclerosis from multi-shell diffusion MRI

Irreversible white matter (WM) damage, including severe demyelination and axonal loss, is a main determinant of long-term disability in multiple sclerosis (MS). Non-invasive detection of changes in microstructural WM integrity in the disease is challenging since commonly used imaging metrics lack th...

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Detalhes bibliográficos
Publicado no:Neuroimage Clin
Main Authors: De Santis, Silvia, Granberg, Tobias, Ouellette, Russell, Treaba, Constantina A., Herranz, Elena, Fan, Qiuyun, Mainero, Caterina, Toschi, Nicola
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370560/
https://ncbi.nlm.nih.gov/pubmed/30739842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2019.101699
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