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Thymic tolerance as a key brake on autoimmunity

Although the thymus has long been recognized as a key organ for T cell selection, the intricate details linking these selection events to human autoimmunity have been challenging. Over the last two decades, there has been rapid progress in understanding the role of thymic tolerance mechanisms in aut...

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Pubblicato in:Nat Immunol
Autori principali: Cheng, Mickie, Anderson, Mark S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370479/
https://ncbi.nlm.nih.gov/pubmed/29925986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-018-0128-9
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