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Author’s view: epithelial plasticity metabolically reprograms normal cells towards a neoplastic-prone state

We have uncovered that epithelial plasticity programs metabolically reprogram epithelial lung cells by increasing expression of genes (e.g., glutamine-fructose-6-phosphate transaminase 2 – GFPT2 and UDP-N-acetylglucosamine pyrophosphorylase 1 – UAP1) critical for the hexosamine biosynthetic pathway...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Wang, Hailun, Tran, Phuoc T.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370387/
https://ncbi.nlm.nih.gov/pubmed/30788419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2018.1543485
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