Randomized, Placebo-Controlled Trial to Evaluate Effects of Eplerenone on Metabolic and Inflammatory Indices in HIV

CONTEXT: HIV-infected individuals demonstrate increased renin-angiotensin-aldosterone system activation in association with visceral adiposity, insulin resistance, and inflammation. A physiologically based treatment approach targeting mineralocorticoid receptor (MR) blockade may improve metabolic an...

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Pubblicato in:J Clin Endocrinol Metab
Autori principali: Srinivasa, Suman, Fitch, Kathleen V, Wong, Kimberly, O’Malley, Timothy K, Maehler, Patrick, Branch, Karen L, Looby, Sara E, Burdo, Tricia H, Martinez-Salazar, Edgar L, Torriani, Martin, Lyons, Shannon H, Weiss, Julian, Feldpausch, Meghan, Stanley, Takara L, Adler, Gail K, Grinspoon, Steven K
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2018
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Clinical Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370281/
https://ncbi.nlm.nih.gov/pubmed/29659888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2018-00330
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